Feb 15, 2019

Bioinfogate will be showcasing some of their recent developments at the Society of Toxicology’s 58th Annual Meeting and ToxExpo in Baltimore, MD, March 10-14 2019.

At the exhibition (booth 4210), the latest version of our translational safety intelligence portal OFF-X will be presented, including new and forthcoming enhancements like the expansion of the Drugs&Biologics area or the launch of the Additional References section, developed in order to expand the coverage of targets in the system.

A series of case studies will be presented to demonstrate OFF-X’s utility for a wide variety of professionals including:

  • Biologists and Bioinformaticians, to perform new target safety assessment
  • Medicinal Chemists, to identify potential toxicophores and optimize hit compounds
  • Data Scientists, to build predictive and AI models using OFF-X’s high quality curated and structured dataset
  • Toxicologists and Non-Clinical Safety Researchers, to analyze data for regulatory endpoints of interest, assess secondary pharmacology and potential off-target liabilities
  • Clinical Researchers, to optimize clinical trial design, understand mechanistic toxicity of adverse events observed in clinical trials and to benchmark competitors’ safety profiles
  • Pharmacovigilance teams to discover unknown adverse events and support understanding of safety alerts
  • Regulatory professionals, to facilitate mandatory reporting requirements of regulatory bodies
  • Business Development Analysts, to enhance due diligence of potential in-licensing opportunities

Since its launch in 2017, Bioinfogate OFF-X has been providing integrated preclinical toxicity and clinical adverse event intelligence for drugs and targets in all phases of R&D, including first-in-class and emerging targets. OFF-X allows prompt identification of toxicology and safety signals and de-risking of R&D projects. As of February 2019, the portal covers a range of 7,000 targets and 9,000 drugs & biologics, and is populated with more than 260,000 expertly curated safety alerts and 500,000 references of interest associated to 4,000 adverse effects. OFF-X is used across pharma and biotech organizations, in leading research centers and regulatory bodies (for more information visit

For further information or to schedule a meeting during the conference, please contact


About Society of Toxicology (SOT)

SOT, founded in 1961, is a professional and scholarly organization of scientists from academic institutions, government, and industry representing scientists who practice toxicology in the US and abroad. The Society’s mission is to create a safer and healthier world by advancing the science and increasing the impact of toxicology. The SOT Annual Meeting hosts 6,000+ participants from the fields of toxicology, safety, regulation, risk assessment and more.


About Bioinfogate

Bioinfogate is a forward thinking, private company working to solve unmet medical needs. Our innovative data science products support the discovery and development of better and safer drugs. We are committed to building industry-leading solutions and identifying and investing in emerging projects that align with our core business in the life sciences and data analytics.

Our passion and capabilities stem from more than 60 years of experience creating and managing biomedical knowledge, first at Prous Science (1958-2007; acquired by Thomson Reuters in 2007), and then at Prous Institute for Biomedical Research. Bioinfogate is the latest initiative within the Prous family group of companies embracing a long tradition and expertise in scientific knowledge management.