We inspire the scientific community by revealing new gateways in drug R&D

By tapping into our extensive network of thought leaders and harnessing more than 50 years' experience in scientific knowledge management, we are able to identify emerging trends in biomedical research and show how data science is enabling a new paradigm transforming patient care.

Our Insight Reports inspire and help researchers to stay abreast of emerging areas of investigation and trends in drug R&D to rethink the therapeutic future. Insight Reports, along with other products developed by BioInfoGate and the company’s strategic investments, reflect emerging trends in biomedical research.

ups

Our first Insight Report provides a comprehensive review of the Ubiquitin-Proteasom System (UPS). UPS is presented focusing on basic science, diseases, and drug targets

Content

Targeting the Ubiquitin-Proteasome System (UPS) for Drug Discovery.
Introduction: It’s Time to Rethink the Therapeutic Future
Proteasome
Immunoproteasome
E1 Ubiquitin Activating Enzymes
E2 Ubiquitin Conjugating Enzymes
E3 Ubiquitin Ligases
Deubiquitinating Enzymes
SUMOylation
Neddylation
P97 AAA (Valsoin-Contain Protein – VCP)
Protein-Protein Interactions
Information on over 200 genes related to the UPS
UPS Glossary
Causal Loop Diagrams
Disease Cross-Talks

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Available on 02/2017

epi

Available on 05/2017

cancmet

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